Taken together, these total results immensely important that miR-29a down-regulated SUV420H2 protein level through directly binding to its 3-UTR

Taken together, these total results immensely important that miR-29a down-regulated SUV420H2 protein level through directly binding to its 3-UTR. miR-29a promotes breast cancer cells invasion and migration via targeting SUV420H2 We following centered on learning whether miR-29a facilitates breasts cancers cells invasion and migration by repressing SUV420H2 expression. miR-29a overexpression and SUV420H2 knockdown in breast cancer cells promoted their invasion […]

Gu J, Kawai H, Nie L, Kitao H, Wiederschain D, Jochemsen AG, Parant J, Lozano G, Yuan Z-M

Gu J, Kawai H, Nie L, Kitao H, Wiederschain D, Jochemsen AG, Parant J, Lozano G, Yuan Z-M. remain sensitive to nutlin treatment. Key Points Endogenously high levels of Mdm4 inhibit and sequester p53 in AML. Large levels of Mdm4 do not block function of Mdm2 inhibitors in AML. codes for any transcription element central in responding to a myriad […]