Notably, durable responders had a higher peak CAR T-cell:TB ratio compared with nonresponders (=

Notably, durable responders had a higher peak CAR T-cell:TB ratio compared with nonresponders (= .005) or responders who subsequently relapsed within 1 year after treatment (= .01; Figure 1E). the statistical analysis plan and an extensive panel of biomarkers according to an expanded translational biomarker plan. Univariable and multivariable analyses indicated that rapid CAR T-cell expansion commensurate with pretreatment tumor […]

The remaining authors haven’t any disclosures to report

The remaining authors haven’t any disclosures to report. Supporting information Figures S1CS2 Click here for more data document.(150K, pdf) Acknowledgments We are grateful to Fred Roberts, from FujiFilm VisualSonics, Inc, for generous tech support team also to Teresa Bowman, through the Specialized Histopathology Primary, Brigham and Women’s Medical center, Division of Pathology, Boston, MA, for dedicated histological analyses. the extracellular […]