´╗┐Together, these data point to a multifaceted action of BRD7 in regulating the expression of different angiogenic mediators

´╗┐Together, these data point to a multifaceted action of BRD7 in regulating the expression of different angiogenic mediators. Discussion In this report, we describe the identification of BRD7 as a negative regulator Rabbit polyclonal to NAT2 of angiogenesis. Furthermore, overexpression of BRD7 resulted in a bromodomain-dependent induction of NFB-activity and NFB-dependent gene expression, including ICAM1, enabling leukocyteCendothelial interactions. In silico […]